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Friday, June 30, 2006 Prepare for Sterilization Direct sterilization of dirty surfaces can result in sterile dirt or worse yet, dirt that protects pathogens from the sterilization process. Surfaces should be clean prior to sterilization. Click Here for a Solution. (Prepare for Sterilization) Wednesday, June 28, 2006 Clean in Place It is to costly and time-consuming to dissasemble large manufacturing filtration systems or tanks, mixers and blenders for cleaning. Click here for a solution. (Clean in Place) Monday, June 26, 2006 Pipet Cleaning Lab pipets will not deliver and measure accurately or they may contaminate reagents if they are not cleaned. Their narrow tubular shape is difficult to clean. Click here for a solution. (Pipet Cleaning) Friday, June 23, 2006 Titanium Prosthesis Cleaning Titanium prosthetic implantable joints need to be cleaned prior to coating and prior to final cleaning for packaging. Click here for a solution. (Titanium Prosthesis Cleaning) Wednesday, June 21, 2006 Low and Non Volatile Organic Compound VOC cleaners To comply with air quality requlations, the use of low volatile cleaning compounds is often required. Click here for a solution. (Low and Non Volatile Organic Compound VOC cleaners) Monday, June 19, 2006 Rinse Water The wrong quality of rinse water can leave rinse water residues on rinsed surfaces. The last thing to touch the surface before drying is the rinse water.- whatever is in the rinse water can be deposited on the surface if the drying is accomplished by eva. Click here for the solution. (Rinse Water) Friday, June 16, 2006 Lab Accreditation There are several instances where the use of cleaners can impact accreditation of your laboratory. One is to pass inspections by the College of American Pathologists (CAP). Another is water testing labs that must meet State accreditation standards. Click here for more information. (Lab Accreditation) Wednesday, June 14, 2006 Tissue Culture A researcher doing tissue culture was having problems reliably growing cultures. Click here for a solution. (Tissue Culture) Monday, June 12, 2006 Biofouling removal from ultrafilters An in-house waste treatment plant with ultrafiltration kept experiencing rapid fouling of their filters causing excessive need to take the system out of service for cleaning. It was suspected that microbes were growing inside the system and rapidly clogg Click here for a Solution (Biofouling removal from ultrafilters) Friday, June 09, 2006 Stopcock grease removal Silicon oil-based stopcock grease used to assure that ground glass joints and stopcocks did not freeze got onto glassware and could not be removed by standard cleaners. Click here for a Solution (Stopcock grease removal) Wednesday, June 07, 2006 Milkstone Removal A dairy lab using milk pipets would get a white, crusty milkstone buildup on the pipets that could not be removed by standard alkaline cleaners. Click here for the solution. (Milkstone Removal) Monday, June 05, 2006 Cold Filtered Beer, Filter Cleaning Residues from fermentation fouled the filters used in cold filtering beer. Since some of these residues are proteins, standard caustic and acid cleaners caused denaturing and cross-linking of the proteins, thereby making them even more difficult to clean. Click here for a solution. (Cold Filtered Beer, Filter Cleaning) Thursday, June 01, 2006 US College of American Pathologists CAP Lab Accreditation As part of the US College of American Pathologists CAP Lab Accreditation questionnaire, a lab must detail how they measure cleanliness on glassware. Click here for a glassware cleaning solution. (US College of American Pathologists CAP Lab Accreditation)

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